AMH

Across TCGA cell cohorts, AMH RNA expression is significantly associated with the go_rna of many other GO terms, with 3,109 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AMH-associated GO terms across cancer lineages are Negative regulation of ovarian follicle development, Regulation of ovarian follicle development, and Positive regulation of double-strand break repair. Each is linked with AMH in more than 18 cancer types. Because this analysis shows association rather than direction, both AMH-to-partner and partner-to-AMH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ovarian follicle development grouped by AMH-low versus AMH-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMH→partner) and Y-score (partner→AMH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of ovarian follicle development →	+1.664	+2.801	<.001	<.001	3	19
LIVER	Regulation of ovarian follicle development →	-0.185	-1.753	.003	.003	3	14
BONE	Positive regulation of double-strand break repair →	+0.087	+2.145	<.001	.001	3	11
SKIN	Negative regulation of chromosome organization →	+0.091	+1.992	<.001	<.001	3	11
BLOOD_Leukemia	Replication fork processing →	+0.078	+1.581	<.001	<.001	3	11
BONE	Positive regulation of DNA metabolic process →	+0.089	+2.052	.003	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,109 associations by consensus.

Negative regulation of ovarian follicle development by AMH expression — BLOOD_Myeloma

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