AMH

Across TCGA pan-cancer cohorts, AMH RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of AMH’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where AMH RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AMH is over-expressed in tumor.

COAD, BLCA, and HNSC are the cancer types where AMH tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AMH RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+2.564	<.001	10	view →
BLCA	Male	All	+1.904	<.001	10	view →
HNSC	All	III,IV	+0.623	<.001	8	view →
STAD	All	All	+1.511	<.001	7	view →
KIRC	Male	All	+0.354	<.001	7	view →
UCEC	All	All	+2.420	<.001	6	view →
KIRP	All	III,IV	+1.317	<.001	6	view →
BRCA	All	III,IV	+0.864	<.001	6	view →
ESCA	All	All	+2.135	<.001	5	view →
LUSC	All	All	+0.716	<.001	5	view →
LIHC	All	All	+0.425	.001	4	view →
CHOL	All	All	+1.863	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

AMH–COAD

Open the COAD breakdown →