AMH

Across TCGA cell cohorts, AMH mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AMH-associated genes across cancer lineages are GPR119, FGF6, and SLCO1C1. Each is linked with AMH in more than 1 cancer types. Because this analysis shows association rather than direction, both AMH-to-partner and partner-to-AMH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR119 grouped by AMH-low versus AMH-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMH→partner) and Y-score (partner→AMH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GPR119 →	+0.025	+4.867	<.001	.009	3	2
CNS	FGF6 →	+0.067	+4.981	<.001	.008	3	2
LARGE_INTESTINE	SLCO1C1 →	+0.434	+3.464	<.001	.004	3	2
BLOOD_Lymphoma	NOBOX →	+0.006	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	KLHL40 →	+0.013	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	MRGPRE →	+0.019	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

GPR119 by AMH expression — BLOOD_Lymphoma

Explore this box plot interactively →