AMBP

Across TCGA patient cohorts, AMBP mutation is significantly associated with the RNA expression of many other genes, with 2,008 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMBP-associated genes across cancer lineages are SLC5A4P1, RN7SL132P, and MIR193BHG. Each is linked with AMBP in more than 1 cancer types. Because this analysis shows association rather than direction, both AMBP-to-partner and partner-to-AMBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A4P1 grouped by AMBP-low versus AMBP-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMBP→partner) and Y-score (partner→AMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC5A4P1 →	+0.066	+4.984	<.001	.005	3	2
COAD	RN7SL132P →	+1.039	+3.870	<.001	.004	3	2
SKCM	MIR193BHG →	+0.654	+2.925	<.001	.001	3	2
UCEC	MYO19 →	+0.533	+3.524	.001	.002	3	2
SKCM	UNGP3 →	+0.149	+2.081	.001	.005	3	2
UCEC	ZMYND19 →	+0.480	+3.119	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,008 associations by consensus.

SLC5A4P1 by AMBP expression — LUAD

Explore this box plot interactively →