ALX3

Across TCGA patient cohorts, ALX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,856 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible ALX3-associated GO terms across cancer lineages are Kidney epithelium development, Obsolete positive regulation of histone methylation, and Neural tube development. Each is linked with ALX3 in more than 16 cancer types. Because this analysis shows association rather than direction, both ALX3-to-partner and partner-to-ALX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Kidney epithelium development grouped by ALX3-low versus ALX3-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALX3→partner) and Y-score (partner→ALX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Kidney epithelium development →	+0.058	+0.469	<.001	<.001	3	17
ESCA	Obsolete positive regulation of histone methylation →	+0.046	+0.398	<.001	<.001	3	17
ESCA	Neural tube development →	+0.045	+0.590	<.001	<.001	3	17
ESCA	Obsolete regulation of histone H3-K4 methylation →	+0.065	+0.653	<.001	<.001	3	16
TGCT	Establishment of tissue polarity →	+0.068	+0.446	<.001	<.001	3	16
TGCT	Positive regulation of Wnt signaling pathway →	+0.044	+0.437	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,856 associations by consensus.

Kidney epithelium development by ALX3 expression — TGCT

Explore this box plot interactively →