ALX3

Across TCGA patient cohorts, ALX3 mutation is significantly associated with the RNA expression of many other genes, with 178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALX3-associated genes across cancer lineages are UBE2CP4, LINC01784, and DLGAP5P2. Each is linked with ALX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALX3-to-partner and partner-to-ALX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2CP4 grouped by ALX3-low versus ALX3-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALX3→partner) and Y-score (partner→ALX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	UBE2CP4 →	+0.205	+5.060	<.001	.008	3	2
PRAD	LINC01784 →	+0.104	+7.939	<.001	.008	3	2
PRAD	DLGAP5P2 →	+0.084	+7.939	<.001	.008	3	2
SKCM	MIR3668 →	+0.256	+4.475	<.001	.005	3	2
KIRP	UBE2V1P9 →	+0.154	+5.376	<.001	.005	3	2
KIRP	RN7SL795P →	+0.157	+5.060	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 178 associations by consensus.

UBE2CP4 by ALX3 expression — KIRP

Explore this box plot interactively →