ALX1

Across TCGA cell cohorts, ALX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,414 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ALX1-associated GO terms across cancer lineages are Epithelial cell development, Dopamine uptake involved in synaptic transmission, and Calcium-dependent cell-cell adhesion. Each is linked with ALX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALX1-to-partner and partner-to-ALX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cell development grouped by ALX1-low versus ALX1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALX1→partner) and Y-score (partner→ALX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epithelial cell development →	-0.113	-1.896	<.001	<.001	3	8
SOFT_TISSUE	Dopamine uptake involved in synaptic transmission →	+1.063	+1.920	.006	<.001	3	7
SKIN	Calcium-dependent cell-cell adhesion →	-0.270	-2.168	<.001	<.001	3	7
URINARY_TRACT	Regulation of endothelial cell chemotaxis →	-0.124	-0.619	<.001	.009	3	7
BONE	Amino acid activation →	+0.106	+2.095	.001	<.001	3	7
BONE	tRNA aminoacylation →	+0.106	+2.095	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,414 associations by consensus.

Epithelial cell development by ALX1 expression — BONE

Explore this box plot interactively →