ALPK3

Across TCGA patient cohorts, ALPK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,205 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ALPK3-associated proteins across cancer lineages are ALPK3_S1855, ALPK3_S1865, and EFEMP2. Each is linked with ALPK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ALPK3-to-partner and partner-to-ALPK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALPK3 versus ALPK3_S1855 in LUAD, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPK3→partner) and Y-score (partner→ALPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ALPK3_S1855 →	+1.636	+1.757	<.001	<.001	3	7
HNSC	ALPK3_S1865 →	+1.432	+0.892	<.001	<.001	3	6
BRCA	EFEMP2 →	+0.488	+0.527	<.001	<.001	3	5
OV	SERPINF1 →	+0.777	+0.775	.001	<.001	3	4
BRCA	UTRN →	+0.372	+1.011	<.001	<.001	3	4
HNSC	HNMT →	+0.572	+0.856	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,205 associations by consensus.

ALPK3 vs ALPK3_S1855 — LUAD

Explore this scatter interactively →