ALPK3

Across TCGA cell cohorts, ALPK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,662 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ALPK3-associated GO terms across cancer lineages are Regulation of mRNA processing, Regulatory ncRNA-mediated gene silencing, and Negative regulation of myoblast fusion. Each is linked with ALPK3 in more than 10 cancer types. Because this analysis shows association rather than direction, both ALPK3-to-partner and partner-to-ALPK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by ALPK3-low versus ALPK3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPK3→partner) and Y-score (partner→ALPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA processing →	+0.094	+2.438	<.001	<.001	3	11
SOFT_TISSUE	Regulatory ncRNA-mediated gene silencing →	+0.109	+2.588	<.001	<.001	3	10
OVARY	Negative regulation of myoblast fusion →	+0.115	+0.933	<.001	.008	3	10
BLOOD_Lymphoma	Positive regulation of autophagy →	+0.043	+0.242	<.001	.001	3	9
BLOOD_Lymphoma	Protein targeting →	+0.038	+0.245	.005	<.001	1	11
URINARY_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.077	+1.378	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,662 associations by consensus.

Regulation of mRNA processing by ALPK3 expression — SOFT_TISSUE

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