ALPK1

Across TCGA patient cohorts, ALPK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,420 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALPK1-associated proteins across cancer lineages are NFKB1, PML, and ALPK1_S721. Each is linked with ALPK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALPK1-to-partner and partner-to-ALPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALPK1 versus NFKB1 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPK1→partner) and Y-score (partner→ALPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NFKB1 →	+0.297	+0.650	<.001	<.001	3	6
GBM	PML →	+0.434	+0.663	<.001	<.001	3	6
GBM	ALPK1_S721 →	+1.832	+1.552	.004	.002	3	6
OV	WDR1 →	+0.425	+0.814	.001	<.001	3	6
UCEC	HLA-DMA →	+1.072	+0.510	<.001	<.001	3	6
HNSC	LGALS9 →	+0.650	+0.665	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,420 associations by consensus.

ALPK1 vs NFKB1 — BRCA

Explore this scatter interactively →