ALPK1

Across TCGA patient cohorts, ALPK1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,250 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALPK1-associated genes across cancer lineages are RTEL1P1, LYN, and TLR6. Each is linked with ALPK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALPK1-to-partner and partner-to-ALPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALPK1 versus RTEL1P1 in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPK1→partner) and Y-score (partner→ALPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RTEL1P1 →	+0.870	+0.859	.002	.002	3	5
GBM	LYN →	+0.718	+0.668	<.001	<.001	3	5
GBM	TLR6 →	+0.973	+0.806	<.001	<.001	3	5
CCRCC	GOLGA5P1 →	+1.113	+0.509	<.001	<.001	3	5
GBM	FYB1 →	+1.217	+0.557	<.001	<.001	3	5
HNSC	TNFSF13B →	+1.366	+1.070	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,250 associations by consensus.

ALPK1 vs RTEL1P1 — HNSC

Explore this scatter interactively →