ALPI

Across TCGA patient cohorts, ALPI protein abundance is significantly associated with the RNA expression of many other genes, with 708 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ALPI-associated genes across cancer lineages are SLC14A1, RNU6-103P, and SMCR2. Each is linked with ALPI in more than 1 cancer types. Because this analysis shows association rather than direction, both ALPI-to-partner and partner-to-ALPI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALPI versus SLC14A1 in PDAC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPI→partner) and Y-score (partner→ALPI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC14A1 →	-1.459	-1.822	.003	<.001	3	1
PDAC	RNU6-103P →	-0.559	-1.308	.003	.003	3	1
PDAC	SMCR2 →	-0.164	-1.324	.008	.001	3	1
PDAC	PABPC1P8 →	+0.041	+1.374	.007	.007	3	1
PDAC	LINC02639 →	-0.115	-1.546	.002	.001	3	1
PDAC	LINC01496 →	-0.080	-1.529	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 708 associations by consensus.

ALPI vs SLC14A1 — PDAC

Explore this scatter interactively →