ALPI

Across TCGA cell cohorts, ALPI RNA expression is significantly associated with the go_rna of many other GO terms, with 570 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALPI-associated GO terms across cancer lineages are Blastocyst growth, Negative regulation of Arp2/3 complex-mediated actin nucleation, and Fructose catabolic process. Each is linked with ALPI in more than 3 cancer types. Because this analysis shows association rather than direction, both ALPI-to-partner and partner-to-ALPI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blastocyst growth grouped by ALPI-low versus ALPI-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPI→partner) and Y-score (partner→ALPI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Blastocyst growth →	-0.141	-0.638	.001	.001	3	4
CNS	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.123	+0.007	.001	.007	3	4
LARGE_INTESTINE	Fructose catabolic process →	+0.250	+0.975	<.001	.001	3	4
LARGE_INTESTINE	Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate →	+0.250	+0.975	<.001	.001	3	4
LARGE_INTESTINE	Aerobic respiration →	+0.046	+0.572	<.001	.001	3	3
LARGE_INTESTINE	Positive regulation of platelet-derived growth factor receptor signaling pathway →	-0.245	-0.554	.008	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 570 associations by consensus.

Blastocyst growth by ALPI expression — LARGE_INTESTINE

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