ALPG

Across TCGA patient cohorts, ALPG RNA expression is significantly associated with the go_rna of many other GO terms, with 6,354 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible ALPG-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Phosphatidylethanolamine acyl-chain remodeling, and Acetylcholine secretion. Each is linked with ALPG in more than 7 cancer types. Because this analysis shows association rather than direction, both ALPG-to-partner and partner-to-ALPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription by RNA polymerase I grouped by ALPG-low versus ALPG-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPG→partner) and Y-score (partner→ALPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Transcription by RNA polymerase I →	+0.026	+1.570	<.001	.002	3	8
PAAD	Phosphatidylethanolamine acyl-chain remodeling →	+0.058	+1.162	<.001	<.001	3	8
ESCA	Acetylcholine secretion →	+0.287	+1.359	<.001	<.001	3	7
ESCA	Riboflavin metabolic process →	+0.103	+1.301	<.001	<.001	3	7
TGCT	RNA 5'-end processing →	+0.038	+2.117	<.001	<.001	3	7
LUSC	Regulation of exocytosis →	+0.015	+0.305	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,354 associations by consensus.

Transcription by RNA polymerase I by ALPG expression — TGCT

Explore this box plot interactively →