ALOX12P1

Across TCGA pan-cancer cohorts, ALOX12P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ALOX12P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ALOX12P1 RNA is repressed in tumor relative to normal tissue. In most cancer types ALOX12P1 is over-expressed in tumor, although a few such as LUAD and KIRC show the opposite, repressed pattern.

LUAD, KIRC, and LUSC are the cancer types where ALOX12P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALOX12P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.085	.001	2	view →
KIRC	All	III,IV	−0.023	.002	2	view →
LUSC	All	All	+0.027	.049	1	view →
LIHC	All	All	+0.021	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ALOX12P1–LUAD

Open the LUAD breakdown →