ALOX12B

Across TCGA patient cohorts, ALOX12B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,128 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALOX12B-associated proteins across cancer lineages are CASP8, NDRG4, and MAPKAPK2. Each is linked with ALOX12B in more than 3 cancer types. Because this analysis shows association rather than direction, both ALOX12B-to-partner and partner-to-ALOX12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALOX12B versus CASP8 in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX12B→partner) and Y-score (partner→ALOX12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CASP8 →	-0.452	-0.147	<.001	<.001	3	4
HNSC	NDRG4 →	+0.933	+1.513	<.001	<.001	3	4
GBM	MAPKAPK2 →	-0.329	-0.158	<.001	<.001	3	4
GBM	ARPC1B →	-0.455	-0.116	.002	.004	3	3
GBM	ARPC5 →	-0.305	-0.140	<.001	<.001	3	3
LSCC	BAIAP2 →	+0.775	+1.007	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,128 associations by consensus.

ALOX12B vs CASP8 — GBM

Explore this scatter interactively →