ALOX12B

Across TCGA patient cohorts, ALOX12B protein abundance is significantly associated with the RNA expression of many other genes, with 891 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ALOX12B-associated genes across cancer lineages are PABPN1, RIMS4, and SALL4. Each is linked with ALOX12B in more than 1 cancer types. Because this analysis shows association rather than direction, both ALOX12B-to-partner and partner-to-ALOX12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALOX12B versus PABPN1 in HNSC, with a Pearson correlation of -0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX12B→partner) and Y-score (partner→ALOX12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PABPN1 →	-0.502	-0.519	.006	.006	3	1
HNSC	RIMS4 →	-0.479	-0.638	.004	.004	3	1
HNSC	SALL4 →	-0.773	-0.484	<.001	.002	3	1
HNSC	SYNDIG1 →	-1.106	-0.808	.002	.003	3	1
HNSC	SRPX2 →	-0.446	-0.490	.003	.002	3	1
HNSC	SYTL4 →	-0.656	-0.757	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 891 associations by consensus.

ALOX12B vs PABPN1 — HNSC

Explore this scatter interactively →