ALOX12B

Across TCGA cell cohorts, ALOX12B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,057 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ALOX12B-associated GO terms across cancer lineages are Cytoplasmic translational initiation, Aminoacyl-tRNA metabolism involved in translational fidelity, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with ALOX12B in more than 7 cancer types. Because this analysis shows association rather than direction, both ALOX12B-to-partner and partner-to-ALOX12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translational initiation grouped by ALOX12B-low versus ALOX12B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX12B→partner) and Y-score (partner→ALOX12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytoplasmic translational initiation →	+0.078	+0.669	<.001	.002	3	8
CNS	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.078	+0.322	<.001	<.001	3	7
STOMACH	Positive regulation of telomerase RNA localization to Cajal body →	+0.086	+0.854	.001	.003	2	8
OESOPHAGUS	Cytoplasmic translation →	+0.084	+1.054	.007	.004	2	8
BLOOD_Lymphoma	Regulation of mucus secretion →	+0.444	+0.824	<.001	<.001	3	7
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.049	+0.491	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,057 associations by consensus.

Cytoplasmic translational initiation by ALOX12B expression — STOMACH

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