ALOX12

Across TCGA patient cohorts, ALOX12 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,495 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALOX12-associated proteins across cancer lineages are METTL16, PHF23, and PPP1R18_S368. Each is linked with ALOX12 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALOX12-to-partner and partner-to-ALOX12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALOX12 versus METTL16 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX12→partner) and Y-score (partner→ALOX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	METTL16 →	+0.217	+0.306	<.001	<.001	3	4
OV	PHF23 →	+0.400	+0.476	<.001	.002	3	4
GBM	PPP1R18_S368 →	-0.503	-0.389	<.001	<.001	3	3
LSCC	AQR →	+0.297	+0.514	<.001	<.001	3	3
HNSC	NCOR1_S2184 →	+0.509	+0.735	<.001	.003	3	3
LSCC	USP39 →	+0.270	+0.475	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,495 associations by consensus.

ALOX12 vs METTL16 — GBM

Explore this scatter interactively →