ALOX12

Across TCGA cell cohorts, ALOX12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,461 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ALOX12-associated GO terms across cancer lineages are mRNA splice site recognition, Negative regulation of myoblast fusion, and Negative regulation of telomere maintenance. Each is linked with ALOX12 in more than 13 cancer types. Because this analysis shows association rather than direction, both ALOX12-to-partner and partner-to-ALOX12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by ALOX12-low versus ALOX12-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX12→partner) and Y-score (partner→ALOX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	mRNA splice site recognition →	+0.126	+0.302	.003	.007	3	14
BONE	Negative regulation of myoblast fusion →	+0.107	+0.213	<.001	.002	3	11
BONE	Negative regulation of telomere maintenance →	+0.080	+0.201	<.001	.002	3	11
BONE	Negative regulation of RNA splicing →	+0.102	+0.171	<.001	<.001	3	11
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.106	+0.214	<.001	.001	3	11
BONE	Microtubule nucleation →	+0.126	+0.205	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,461 associations by consensus.

mRNA splice site recognition by ALOX12 expression — STOMACH

Explore this box plot interactively →