ALKBH6

Across TCGA patient cohorts, ALKBH6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,816 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALKBH6-associated proteins across cancer lineages are SF3B3, UBA2, and SAE1. Each is linked with ALKBH6 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALKBH6-to-partner and partner-to-ALKBH6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH6 versus SF3B3 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH6→partner) and Y-score (partner→ALKBH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SF3B3 →	+0.191	+0.314	<.001	<.001	3	6
PDAC	UBA2 →	+0.274	+0.317	<.001	<.001	3	6
HNSC	SAE1 →	+0.320	+0.664	<.001	<.001	3	5
LSCC	SUPT6H →	+0.220	+0.503	.003	<.001	3	5
OV	TBCB →	+0.427	+0.513	.001	.002	3	5
HNSC	TAF6L →	+0.235	+0.416	.008	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,816 associations by consensus.

ALKBH6 vs SF3B3 — PDAC

Explore this scatter interactively →