ALKBH6

Across TCGA patient cohorts, ALKBH6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,493 significant associations in total. OV shows the largest number of these associations.

The most reproducible ALKBH6-associated genes across cancer lineages are GPI, ATP5PD, and RPL13AP6. Each is linked with ALKBH6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALKBH6-to-partner and partner-to-ALKBH6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH6 versus GPI in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH6→partner) and Y-score (partner→ALKBH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GPI →	+1.000	+0.369	.001	.003	3	3
HNSC	ATP5PD →	+0.466	+0.480	.003	<.001	3	3
OV	RPL13AP6 →	-1.382	-0.344	<.001	.002	3	3
HNSC	UBQLN4 →	+0.479	+0.486	<.001	.002	3	2
BRCA	CACNB3 →	-0.575	-0.335	.001	.003	3	2
UCEC	LINC00471 →	+0.702	+0.382	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,493 associations by consensus.

ALKBH6 vs GPI — HNSC

Explore this scatter interactively →