ALKBH6

Across TCGA cell cohorts, ALKBH6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,740 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ALKBH6-associated GO terms across cancer lineages are Tubulin deacetylation, Process utilizing autophagic mechanism, and Autophagy. Each is linked with ALKBH6 in more than 11 cancer types. Because this analysis shows association rather than direction, both ALKBH6-to-partner and partner-to-ALKBH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tubulin deacetylation grouped by ALKBH6-low versus ALKBH6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH6→partner) and Y-score (partner→ALKBH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Tubulin deacetylation →	+0.152	+0.573	<.001	.002	3	12
SOFT_TISSUE	Process utilizing autophagic mechanism →	+0.041	+0.575	<.001	<.001	3	11
SOFT_TISSUE	Autophagy →	+0.041	+0.575	<.001	<.001	3	11
SOFT_TISSUE	Macroautophagy →	+0.043	+0.655	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of intralumenal vesicle formation →	+0.166	+0.596	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of proteasomal protein catabolic process →	+0.048	+0.814	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,740 associations by consensus.

Tubulin deacetylation by ALKBH6 expression — BONE

Explore this box plot interactively →