ALKBH6

Across TCGA cell cohorts, ALKBH6 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALKBH6-associated genes across cancer lineages are CD300H and CPLX4. Each is linked with ALKBH6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALKBH6-to-partner and partner-to-ALKBH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by ALKBH6-low versus ALKBH6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH6→partner) and Y-score (partner→ALKBH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CPLX4 →	+0.053	+4.392	<.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD300H by ALKBH6 expression — LARGE_INTESTINE

Explore this box plot interactively →