ALG6

Across TCGA patient cohorts, ALG6 mutation is significantly associated with the RNA expression of many other genes, with 1,889 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG6-associated genes across cancer lineages are RN7SL248P, IL21, and YBX1P9. Each is linked with ALG6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALG6-to-partner and partner-to-ALG6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ALG6-low versus ALG6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG6→partner) and Y-score (partner→ALG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.056	+3.059	<.001	.005	3	3
UCEC	IL21 →	+0.103	+2.026	.003	.001	3	2
CESC	YBX1P9 →	+0.064	+5.010	<.001	.009	3	2
CESC	RNU1-17P →	+0.371	+5.103	<.001	.008	3	2
STAD	MIR507 →	+0.462	+4.401	.002	.006	3	2
STAD	RNU7-46P →	+1.178	+4.254	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,889 associations by consensus.

RN7SL248P by ALG6 expression — UCEC

Explore this box plot interactively →