ALG3

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ALG3 mutation is significantly associated with the mutation status of many other genes, with 5,784 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALG3-associated genes across cancer lineages are PI4KA, SYNRG, and KDM2B. Each is linked with ALG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALG3-to-partner and partner-to-ALG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG3→partner) and Y-score (partner→ALG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPI4KA →+3.635+4.392<.001<.00113
LARGE_INTESTINESYNRG →+2.728+2.597<.001<.00113
LARGE_INTESTINEKDM2B →+2.635+3.963<.001<.00113
BLOOD_LymphomaNWD1 →+4.429+5.247.005.00513
BLOOD_LymphomaFAM111B →+4.429+5.247.005.00513
LARGE_INTESTINEPHLDB1 →+1.857+1.925.006.00613
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,784 associations by consensus.

Exploration