ALG2

Across TCGA patient cohorts, ALG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,154 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG2-associated proteins across cancer lineages are C9orf64, FAM120A, and GOLGA1. Each is linked with ALG2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALG2-to-partner and partner-to-ALG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG2 versus C9orf64 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG2→partner) and Y-score (partner→ALG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C9orf64 →	+0.382	+0.392	<.001	.003	3	8
BRCA	FAM120A →	+0.250	+0.316	<.001	.002	3	8
OV	GOLGA1 →	+0.302	+0.388	<.001	<.001	3	8
OV	TDRD7 →	+0.468	+0.487	<.001	<.001	3	7
BRCA	SEC16A →	+0.225	+0.330	.001	.002	3	7
BRCA	PSMD5 →	+0.307	+0.440	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,154 associations by consensus.

ALG2 vs C9orf64 — OV

Explore this scatter interactively →