ALG1L6P

Across TCGA pan-cancer cohorts, ALG1L6P RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated ALG1L6P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ALG1L6P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ALG1L6P expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

KIRC, UVM, and KICH are the cancer types where ALG1L6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	II,III,IV	0.611	0.775	<.001	118	view →
UVM	OS	Median	All	0.825	0.428	<.001	88	view →
KICH	DFS	Median	II,III,IV	0.558	1.000	.003	73	view →
UCS	DFS	Median	II,III,IV	0.421	0.183	.013	60	view →
ACC	DFS	Tertile	All	0.256	0.660	.002	52	view →
COAD	DFS	Quartile	All	0.411	0.751	<.001	51	view →
LIHC	DFS	Quartile	All	0.380	0.575	<.001	51	view →
UCEC	OS	Median	All	0.895	0.955	.001	44	view →
LGG	OS	Median	All	0.742	0.917	<.001	29	view →
MESO	DFS	Quartile	II,III,IV	0.294	0.537	.022	21	view →
LUSC	DFS	Tertile	III,IV	0.421	0.935	.008	20	view →
READ	OS	Quartile	All	0.979	0.838	.009	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

ALG1L6P–KIRC (OS)

Open the KIRC breakdown →