ALG1L14P

Across TCGA pan-cancer cohorts, ALG1L14P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ALG1L14P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ALG1L14P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ALG1L14P expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

HNSC, DLBC, and CESC are the cancer types where ALG1L14P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	III,IV	0.809	0.635	.003	34	view →
DLBC	OS	Tertile	All	0.204	0.936	<.001	30	view →
CESC	OS	Tertile	II,III,IV	0.888	0.701	.019	30	view →
LUAD	OS	Median	II,III,IV	0.636	0.804	.004	25	view →
THCA	OS	Median	IV	0.562	0.924	.009	24	view →
LIHC	DFS	Tertile	All	0.416	0.587	.002	21	view →
READ	OS	Quartile	All	0.798	0.940	.004	21	view →
LGG	DFS	Median	All	0.910	0.781	.002	19	view →
CHOL	OS	Median	All	0.906	0.610	.010	9	view →
KIRP	OS	Quartile	All	0.933	0.618	.015	9	view →
SARC	OS	Tertile	All	0.693	0.391	.011	8	view →
STAD	OS	Quartile	All	0.540	0.311	.037	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ALG1L14P–HNSC (DFS)

Open the HNSC breakdown →