ALG1L11P

Across TCGA pan-cancer cohorts, ALG1L11P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of ALG1L11P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where ALG1L11P RNA is repressed in tumor relative to normal tissue. In most cancer types ALG1L11P is over-expressed in tumor, although a few such as BRCA and READ show the opposite, repressed pattern.

BRCA, PAAD, and READ are the cancer types where ALG1L11P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALG1L11P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.259	<.001	4	view →
PAAD	Female	All	+0.405	.009	2	view →
READ	All	All	−0.229	.006	2	view →
HNSC	Female	All	−0.138	.008	2	view →
KIRC	All	All	−0.072	.007	2	view →
CHOL	Female	All	+0.740	.023	1	view →
THCA	All	All	−0.118	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

ALG1L11P–BRCA

Open the BRCA breakdown →