Across TCGA patient cohorts, ALG1L mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG1L-associated genes across cancer lineages are RN7SKP202, TUBBP11, and NOL12. Each is linked with ALG1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ALG1L-to-partner and partner-to-ALG1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG1L→partner) and Y-score (partner→ALG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP202 →	+0.185	+5.010	<.001	.009	3	2
BLCA	TUBBP11 →	+0.217	+4.691	<.001	.001	3	2
UCEC	NOL12 →	+0.363	+3.732	.007	<.001	3	1
UCEC	MIR8082 →	+0.405	+2.713	<.001	.002	3	1
UCEC	RN7SL478P →	+0.219	+2.354	.003	.003	3	1
CESC	LYZL1 →	+0.059	+5.418	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

Exploration

ALG1L survival (RNA) · tumor vs normal (RNA) · all ALG1L data types