Across TCGA cell cohorts, ALG1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,329 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALG1L-associated GO terms across cancer lineages are Response to indole-3-methanol, Cellular response to alcohol, and Regulation of potassium ion import. Each is linked with ALG1L in more than 7 cancer types. Because this analysis shows association rather than direction, both ALG1L-to-partner and partner-to-ALG1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG1L→partner) and Y-score (partner→ALG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to indole-3-methanol →	+0.189	+2.163	.005	<.001	3	8
LUNG_NSCLC_LUSC	Cellular response to alcohol →	+0.099	+1.822	.004	.009	3	8
LUNG_SCLC	Regulation of potassium ion import →	+0.193	+1.894	.001	.001	3	7
OESOPHAGUS	Regulation of glutamate secretion, neurotransmission →	-0.180	-2.348	<.001	.003	3	7
LUNG_NSCLC_LUSC	Positive regulation of IRE1-mediated unfolded protein response →	+0.143	+2.312	<.001	.003	3	7
PANCREAS	Cellular respiration →	+0.045	+1.482	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,329 associations by consensus.

Exploration

ALG1L survival (RNA) · tumor vs normal (RNA) · all ALG1L data types