ALG14

Across TCGA patient cohorts, ALG14 protein abundance is significantly associated with the RNA expression of many other genes, with 11,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG14-associated genes across cancer lineages are NPRL3, ANP32B, and EIF5B. Each is linked with ALG14 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALG14-to-partner and partner-to-ALG14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG14 versus NPRL3 in HNSC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG14→partner) and Y-score (partner→ALG14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NPRL3 →	-0.656	-0.290	.003	.005	3	4
LSCC	ANP32B →	-0.715	-0.368	.001	<.001	3	4
CCRCC	EIF5B →	-0.524	-0.530	<.001	<.001	3	4
HNSC	PROSER3 →	-0.595	-0.269	.005	.001	3	4
LSCC	SRP68 →	-0.555	-0.412	<.001	<.001	3	4
PDAC	ATXN2L →	-0.602	-0.491	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,216 associations by consensus.

ALG14 vs NPRL3 — HNSC

Explore this scatter interactively →