ALG14-AS1

Across TCGA pan-cancer cohorts, ALG14-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ALG14-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ALG14-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ALG14-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, HNSC, and CHOL are the cancer types where ALG14-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALG14-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	III,IV	−0.080	.001	2	view →
HNSC	All	All	+0.036	.014	2	view →
CHOL	Female	All	+0.153	.042	1	view →
LIHC	Male	All	+0.047	.027	1	view →
KIRC	All	All	−0.026	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ALG14-AS1–KICH

Open the KICH breakdown →