ALDOA

Across TCGA patient cohorts, ALDOA mutation is significantly associated with the RNA expression of many other genes, with 879 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDOA-associated genes across cancer lineages are OR51C4P, OR10AA1P, and LINC00489. Each is linked with ALDOA in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDOA-to-partner and partner-to-ALDOA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51C4P grouped by ALDOA-low versus ALDOA-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDOA→partner) and Y-score (partner→ALDOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR51C4P →	+0.016	+5.263	<.001	.001	3	2
CESC	OR10AA1P →	+0.030	+3.786	<.001	.003	3	2
HNSC	LINC00489 →	+0.085	+6.111	<.001	.002	3	2
HNSC	MIR6842 →	+0.712	+5.182	<.001	.007	3	2
SKCM	SMR3A →	+1.200	+6.199	<.001	.001	3	2
HNSC	TAS2R7 →	+0.089	+5.912	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 879 associations by consensus.

OR51C4P by ALDOA expression — CESC

Explore this box plot interactively →