ALDH9A1

Across TCGA patient cohorts, ALDH9A1 mutation is significantly associated with the RNA expression of many other genes, with 2,471 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH9A1-associated genes across cancer lineages are SNORD114-14, RN7SL159P, and TRDV3. Each is linked with ALDH9A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALDH9A1-to-partner and partner-to-ALDH9A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-14 grouped by ALDH9A1-low versus ALDH9A1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH9A1→partner) and Y-score (partner→ALDH9A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	SNORD114-14 →	+0.548	+4.792	<.001	.006	3	3
COAD	RN7SL159P →	+0.093	+4.136	.004	.008	3	2
COAD	TRDV3 →	+1.420	+4.401	<.001	<.001	3	2
BLCA	RNU6-926P →	+0.298	+7.640	<.001	.009	3	2
LUAD	BLOC1S2P1 →	+0.151	+5.157	<.001	.007	3	2
SARC	COPS8P1 →	+0.107	+5.345	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,471 associations by consensus.

SNORD114-14 by ALDH9A1 expression — LUSC

Explore this box plot interactively →