ALDH7A1P2

Across TCGA pan-cancer cohorts, ALDH7A1P2 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated ALDH7A1P2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ALDH7A1P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ALDH7A1P2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BLCA show a favorable association.

MESO, KIRC, and THCA are the cancer types where ALDH7A1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.130	0.557	.019	54	view →
KIRC	DFS	Tertile	IV	0.283	0.525	.023	33	view →
THCA	OS	Tertile	IV	0.790	0.986	.013	27	view →
CESC	OS	Tertile	II,III,IV	0.270	0.763	.032	18	view →
ESCA	DFS	Tertile	IV	0.704	0.271	.017	16	view →
HNSC	DFS	Tertile	II,III,IV	0.112	0.367	.016	12	view →
BLCA	DFS	Tertile	IV	1.000	0.402	.030	6	view →
SKCM	OS	Tertile	All	0.723	0.330	.024	3	view →
LIHC	DFS	Tertile	II,III,IV	0.835	0.412	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ALDH7A1P2–MESO (OS)

Open the MESO breakdown →