ALDH7A1P2

Across TCGA pan-cancer cohorts, ALDH7A1P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ALDH7A1P2’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where ALDH7A1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types ALDH7A1P2 is over-expressed in tumor, although a few such as ESCA and LUSC show the opposite, repressed pattern.

ESCA and LUSC are the cancer types where ALDH7A1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALDH7A1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	−0.105	.002	3	view →
LUSC	All	All	−0.014	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

ALDH7A1P2–ESCA

Open the ESCA breakdown →