ALDH6A1

Across TCGA patient cohorts, ALDH6A1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,034 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ALDH6A1-associated genes across cancer lineages are PLAUR, GMDS-DT, and ACOT7. Each is linked with ALDH6A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALDH6A1-to-partner and partner-to-ALDH6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH6A1 versus PLAUR in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH6A1→partner) and Y-score (partner→ALDH6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLAUR →	-1.000	-0.505	<.001	<.001	2	8
HNSC	GMDS-DT →	+0.603	+0.450	<.001	<.001	3	7
BRCA	ACOT7 →	-0.547	-0.471	<.001	<.001	3	7
BRCA	KIF14 →	-1.093	-0.666	<.001	<.001	3	6
OV	CALU →	-1.061	-1.076	.002	.003	3	6
BRCA	CEP55 →	-1.195	-0.670	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,034 associations by consensus.

ALDH6A1 vs PLAUR — GBM

Explore this scatter interactively →