ALDH3A2

Across TCGA patient cohorts, ALDH3A2 mutation is significantly associated with the RNA expression of many other genes, with 826 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH3A2-associated genes across cancer lineages are RN7SL248P, GDI2P1, and SS18L2P1. Each is linked with ALDH3A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDH3A2-to-partner and partner-to-ALDH3A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ALDH3A2-low versus ALDH3A2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3A2→partner) and Y-score (partner→ALDH3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL248P →	+0.103	+5.786	<.001	.001	3	2
UCEC	GDI2P1 →	+0.138	+2.379	.001	.003	3	2
UCEC	SS18L2P1 →	+0.317	+2.055	<.001	.006	3	2
UCEC	RNU6-752P →	+0.386	+3.031	<.001	<.001	3	2
COAD	LINC01066 →	+0.218	+5.824	<.001	.001	3	2
COAD	CNOT7P2 →	+0.231	+4.081	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 826 associations by consensus.

RN7SL248P by ALDH3A2 expression — BRCA

Explore this box plot interactively →