ALDH3A1

Across TCGA cell cohorts, ALDH3A1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ALDH3A1-associated genes across cancer lineages are FAM187B, IFNA7, and USP17L11. Each is linked with ALDH3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDH3A1-to-partner and partner-to-ALDH3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM187B grouped by ALDH3A1-low versus ALDH3A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3A1→partner) and Y-score (partner→ALDH3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FAM187B →	+0.080	+4.684	<.001	.002	3	1
SKIN	IFNA7 →	+0.103	+4.273	<.001	.006	3	1
SKIN	USP17L11 →	+0.012	+4.415	<.001	.007	3	1
SKIN	USP17L20 →	+0.012	+4.415	<.001	.007	3	1
SKIN	USP17L18 →	+0.012	+4.415	<.001	.007	3	1
SKIN	OR10G2 →	+0.017	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

FAM187B by ALDH3A1 expression — SKIN

Explore this box plot interactively →