ALDH1L1-AS2

Across TCGA pan-cancer cohorts, ALDH1L1-AS2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ALDH1L1-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ALDH1L1-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ALDH1L1-AS2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.

KIRC, UVM, and KIRP are the cancer types where ALDH1L1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.697	0.556	<.001	141	view →
UVM	OS	Median	All	0.752	0.444	<.001	124	view →
KIRP	DFS	Tertile	II,III,IV	0.755	0.303	<.001	104	view →
MESO	OS	Quartile	III,IV	0.625	0.260	<.001	72	view →
ACC	DFS	Quartile	III,IV	0.619	0.167	.002	53	view →
LGG	OS	Tertile	All	0.279	0.497	<.001	51	view →
ESCA	OS	Tertile	IV	0.143	0.668	.010	30	view →
HNSC	DFS	Tertile	II,III,IV	0.594	0.224	.003	25	view →
THCA	OS	Median	II,III,IV	0.913	0.983	.009	18	view →
READ	DFS	Quartile	II,III,IV	0.294	0.768	.002	18	view →
CHOL	OS	Median	All	0.573	0.945	.005	15	view →
CESC	DFS	Median	III,IV	0.462	0.742	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ALDH1L1-AS2–KIRC (OS)

Open the KIRC breakdown →