ALDH16A1

Across TCGA cell cohorts, ALDH16A1 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALDH16A1-associated genes across cancer lineages are CSN1S1, OR5A1, and IL36B. Each is linked with ALDH16A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDH16A1-to-partner and partner-to-ALDH16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSN1S1 grouped by ALDH16A1-low versus ALDH16A1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH16A1→partner) and Y-score (partner→ALDH16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CSN1S1 →	+0.082	+3.794	.002	.003	3	2
SKIN	OR5A1 →	+0.020	+6.022	<.001	.001	3	1
BLOOD_Lymphoma	IL36B →	+0.032	+5.209	<.001	.005	3	1
BREAST	MYH8 →	+0.022	+4.781	<.001	.003	3	1
BREAST	FAM47B →	+0.012	+4.781	<.001	.003	3	1
STOMACH	SMYD1 →	+0.026	+4.280	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

CSN1S1 by ALDH16A1 expression — STOMACH

Explore this box plot interactively →