AKTIP

Across TCGA patient cohorts, AKTIP protein abundance is significantly associated with the RNA expression of many other genes, with 7,541 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AKTIP-associated genes across cancer lineages are WIPF1, IGF1, and CEP128. Each is linked with AKTIP in more than 3 cancer types. Because this analysis shows association rather than direction, both AKTIP-to-partner and partner-to-AKTIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKTIP versus WIPF1 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKTIP→partner) and Y-score (partner→AKTIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WIPF1 →	-0.723	-0.283	.001	.004	3	4
HNSC	IGF1 →	-1.130	-0.375	<.001	<.001	3	4
HNSC	CEP128 →	-0.562	-0.212	.001	.005	3	3
UCEC	HCK →	-0.905	-0.177	.002	.003	3	3
UCEC	THG1L →	-0.642	-0.181	<.001	<.001	3	3
UCEC	CNTRL →	-0.485	-0.171	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,541 associations by consensus.

AKTIP vs WIPF1 — HNSC

Explore this scatter interactively →