AKTIP

Across TCGA cell cohorts, AKTIP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,372 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKTIP-associated GO terms across cancer lineages are Protein localization to perinuclear region of cytoplasm, Vacuolar transport, and Endosomal transport. Each is linked with AKTIP in more than 16 cancer types. Because this analysis shows association rather than direction, both AKTIP-to-partner and partner-to-AKTIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to perinuclear region of cytoplasm grouped by AKTIP-low versus AKTIP-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKTIP→partner) and Y-score (partner→AKTIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein localization to perinuclear region of cytoplasm →	+0.151	+0.953	<.001	<.001	3	17
URINARY_TRACT	Vacuolar transport →	+0.071	+1.331	<.001	<.001	3	12
BREAST	Endosomal transport →	+0.049	+0.884	.004	.003	2	12
STOMACH	Cellular response to topologically incorrect protein →	+0.069	+0.911	<.001	<.001	3	11
STOMACH	tRNA 5'-end processing →	-0.123	-1.248	<.001	.001	3	10
KIDNEY	Establishment of protein localization to plasma membrane →	+0.066	+0.845	.009	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

Protein localization to perinuclear region of cytoplasm by AKTIP expression — KIDNEY

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