AKT3

Across TCGA cell cohorts, AKT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,835 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible AKT3-associated GO terms across cancer lineages are Intracellular transport of virus, Transport of virus, and Positive regulation of establishment of T cell polarity. Each is linked with AKT3 in more than 11 cancer types. Because this analysis shows association rather than direction, both AKT3-to-partner and partner-to-AKT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular transport of virus grouped by AKT3-low versus AKT3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT3→partner) and Y-score (partner→AKT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Intracellular transport of virus →	+0.172	+1.962	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Transport of virus →	+0.172	+1.962	<.001	<.001	3	12
STOMACH	Positive regulation of establishment of T cell polarity →	+0.265	+3.336	<.001	<.001	3	11
SKIN	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.172	+1.735	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of cytokinesis →	+0.082	+3.048	.009	.005	2	11
STOMACH	Mitotic spindle assembly checkpoint signaling →	+0.132	+2.270	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,835 associations by consensus.

Intracellular transport of virus by AKT3 expression — LUNG_NSCLC_LUAD

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