Across TCGA patient cohorts, AKT3-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,023 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AKT3-IT1-associated proteins across cancer lineages are AKT3, VCL_S346, and YME1L1. Each is linked with AKT3-IT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AKT3-IT1-to-partner and partner-to-AKT3-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT3-IT1→partner) and Y-score (partner→AKT3-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AKT3 →	+0.664	+0.922	<.001	<.001	3	7
LSCC	VCL_S346 →	+0.565	+0.897	<.001	<.001	3	6
UCEC	YME1L1 →	-0.295	-0.809	.003	.001	3	6
HNSC	TCF4 →	+0.496	+0.923	.006	.004	2	7
GBM	PSIP1 →	+0.464	+0.480	<.001	<.001	3	6
UCEC	PSIP1_S129 →	+0.637	+1.270	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,023 associations by consensus.

Exploration

AKT3-IT1 survival (RNA) · tumor vs normal (RNA) · all AKT3-IT1 data types