AKT2

Across TCGA patient cohorts, AKT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,881 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AKT2-associated proteins across cancer lineages are XRCC1, PAFAH1B3, and SAE1. Each is linked with AKT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both AKT2-to-partner and partner-to-AKT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKT2 versus XRCC1 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT2→partner) and Y-score (partner→AKT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	XRCC1 →	+0.395	+0.616	<.001	<.001	3	5
HNSC	PAFAH1B3 →	+0.379	+0.412	<.001	<.001	3	5
GBM	SAE1 →	+0.357	+0.444	<.001	<.001	3	5
GBM	C19orf47 →	+0.384	+0.506	<.001	<.001	3	5
LUAD	TIMM50 →	+0.419	+0.368	.001	<.001	3	5
GBM	CCDC97 →	+0.283	+0.570	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,881 associations by consensus.

AKT2 vs XRCC1 — GBM

Explore this scatter interactively →