AKT1

Across TCGA patient cohorts, AKT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,801 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AKT1-associated proteins across cancer lineages are CDC42BPB, BAG5, and CEP170B. Each is linked with AKT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AKT1-to-partner and partner-to-AKT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKT1 versus CDC42BPB in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT1→partner) and Y-score (partner→AKT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC42BPB →	+0.420	+0.980	<.001	<.001	3	8
GBM	BAG5 →	+0.324	+0.352	<.001	<.001	3	7
BRCA	CEP170B →	+0.358	+0.656	<.001	<.001	3	7
OV	MTA1 →	+0.441	+0.752	<.001	<.001	3	7
GBM	UBR7 →	+0.476	+0.399	<.001	<.001	3	6
LSCC	RCOR1 →	+0.290	+0.367	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,801 associations by consensus.

AKT1 vs CDC42BPB — BRCA

Explore this scatter interactively →