AKR7A2

Across TCGA patient cohorts, AKR7A2 RNA expression is significantly associated with the RNA expression of many other genes, with 18,455 significant associations in total. ACC shows the largest number of these associations.

The most reproducible AKR7A2-associated genes across cancer lineages are UROD, C1orf50, and SLC66A1. Each is linked with AKR7A2 in more than 32 cancer types. Because this analysis shows association rather than direction, both AKR7A2-to-partner and partner-to-AKR7A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKR7A2 versus UROD in PCPG, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR7A2→partner) and Y-score (partner→AKR7A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	UROD →	+0.741	+0.861	<.001	<.001	3	33
ACC	C1orf50 →	+1.086	+1.190	<.001	<.001	3	33
ACC	SLC66A1 →	+0.973	+1.270	<.001	<.001	3	33
KICH	ADPRS →	+0.863	+1.147	<.001	<.001	3	32
CHOL	HMGCL →	+0.881	+0.786	<.001	<.001	3	32
ACC	ERI3 →	+1.011	+1.196	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,455 associations by consensus.

AKR7A2 vs UROD — PCPG

Explore this scatter interactively →